(Article from http://en.wikipedia.org/wiki/SoHo)
SoHo is a neighborhood in the New York City borough of Manhattan. Originally associated with the arts, it has since become famous for both destination shopping and its downtown scene. The name is a blend of "South" and "Houston" from "south of Houston Street." Its name is the model for other new neighborhood acronyms in New York City, such as NoHo, for North of Houston Street, TriBeCa (Triangle Below Canal Street), Nolita (North of Little Italy), and DUMBO (Down Under the Manhattan Bridge Overpass).
It is an archetypal example of inner-city regeneration and gentrification, encompassing socio-economic, cultural, political and architectural developments. Before its incarnation as a trendy locale, it was known as the Cast Iron District because of the many buildings incorporating cast iron architectural elements.